3D cell culture methods — and multicellular tumorspheroids(MCTS), in particular — are quickly becoming a valuable tool for studying the tumor microenvironment incancer research.
癌症科学家正在创造越来越完整模型x tumor models that more accurately replicatein vivoconditions — including the tumor microenvironment, which plays a key role in tumor progression, according to a study published inBioTechniques.
MCTS mimic many of the features that tumors exhibit in the human body, including extracellular matrix (ECM) deposition between cells, gradients in nutrient concentration, and strong cell-cell junctions.